iPad best practices

My laptop died. Boo. I got a new iPad Air. Yay, I guess. How should I set up my privacy, security, and general user preferences? I've had two generations of the iPhone so I'm familiar with iOS, but like all my computers they've devolved into a pile of unusued/forgotten apps and their associated preferences. I'd like to get this iPad off to a good start so I have a few questions:

1. I've noticed some differences, like the absence of certain apps like flickr. What else should I be aware of?
-What security and privacy settings are most important?
2. I've activated Find My iPad. Which iClloud preferences should I be concerned about?
3. I decided to the Chrome browsers on my phone and the iPad, something I didn't do with my laptop. Is there a reason I shouldn't do this?
4. My Apple wireless keyboard works great. The mouse won't sync, but I'll take that to the genius bar. Since this may end up being my primary computer for a while, is there anything else I should use?

iBonus embarrassing question: If I install Candy Crush on the iPad is there any chance I will lose my place in the game or in the game on my phone? I'm on level 344 and would be so bummed if I lost all that progress. :p

Thanks MeFites!

(I realize there may not be agreement across the board. That's fine, I'll take everything under advisement.)